The effect of black cumin consumption on diabetic patients

====================================== Diabetes is one of the most common chronic diseases of this century that millions of people around the world are struggling with. This disease causes an abnormal increase in blood sugar as a result of impaired insulin production or function, and if not controlled, it can cause serious effects on the heart, kidney, eyes and nervous system. Along with drug treatments, lifestyle and nutrition changes play an essential role in diabetes management, and for this reason, the use of medicinal plants as a treatment supplement has attracted the attention of many patients and researchers. Among the medicinal plants, black cumin (Nigella Sativa) has found a special place with its many therapeutic properties, especially in traditional medicine and modern scientific studies. Active compounds such as thymoquinone in black cumin have shown anti-inflammatory, antioxidant and blood sugar regulating effects. This plant not only helps improve insulin function and pancreas health, but can also be effective in controlling blood fat, weight loss, and preventing diabetes complications. What is black cumin? Black cumin or Nigella Sativa is an annual plant of the "Ranunculaceae" family, which originates from Southwest Asia, the Middle East, and parts of North Africa. Due to its black seeds and its medicinal properties, this plant has been used in traditional Iranian, Indian and Islamic medicine for centuries. Black cumin is also known by other names such as "Siyadane", "Shuniz", "Hab al-Suda" or "Black Seed". The seeds of this plant are small, triangular, pure black in color and have a spicy and bitter taste. Its healing properties are also mentioned in the Qur'an, hadiths and ancient texts of Islamic medicine such as Ibn Sina's writings. Ibn Sina in his book "Law of Medicine" mentions black cumin as a medicine for the treatment of many diseases, including strengthening the immune system, regulating digestion and controlling blood sugar**.** The mechanism of action of black cumin in the body of diabetic patients Diabetes is a chronic metabolic disease characterized by an abnormal increase in blood sugar due to impaired insulin function or its deficiency. As a complementary treatment in diabetic patients, black cumin has significant effects on blood sugar control, improving pancreatic function and fighting oxidative damage. These effects are caused by active compounds such as thymoquinone, nigelone and other antioxidant substances in this plant. In the following, we will examine the most important mechanisms of action of black cumin in the body of diabetics: 1. The effect of black cumin on pancreas and insulin production: One of the main mechanisms of black cumin in the body is the direct stimulation of pancreatic beta cells to produce insulin. In type 2 diabetes, although the body still produces insulin, the sensitivity of the cells to this hormone is reduced and the function of the pancreas weakens over time. Laboratory and animal studies have shown that **thymoquinone** - the active ingredient in black cumin - can: - **regenerates and strengthens pancreatic beta cells**. - **Increase the rate of insulin secretion in response to blood sugar**. - **Prevent cell death caused by oxidative stress in pancreatic tissue**. In fact, black cumin both helps increase the natural production of insulin and prevents the destruction of vital pancreatic cells, both of which can play an important role in better blood sugar control. 2. Inhibition of digestive enzymes effective in increasing blood sugar: After eating, carbohydrates are broken down into glucose by enzymes such as alpha-amylase and alpha-glucosidase in the digestive system. This glucose enters the bloodstream and causes an increase in blood sugar after meals. Studies have shown that thymoquinone can: - **inhibit the activity of alpha-amylase enzyme to some extent.** - **Reduce glucose absorption in the small intestine.** - **Causes a gradual decrease in blood sugar after meals (Postprandial Hyperglycemia).** This property of black cumin is very similar to drugs such as acarbose, which are used to lower blood sugar after meals. 3. Reducing oxidative stress in the body of diabetics: Oxidative stress is one of the hidden and important factors in the development of diabetes and its complications. This situation occurs when the amount of free radicals in the body exceeds the capacity of the body's antioxidant defense. In diabetic patients, the level of these radicals is usually high and causes cell destruction, tissue inflammation, damage to kidneys, eyes, blood vessels and nerves. **Black cumin with strong antioxidant compounds such as thymoquinone:** - **Neutralizes free radicals and prevents cell damage.** - **Increases the level of internal antioxidant enzymes such as superoxide dismutase (SOD), glutathione and catalase in the body.** **Reduces chronic inflammation in tissues, which plays a key role in preventing diabetes complications such as neuropathy, nephropathy and retinopathy.** In fact, black cumin is not only effective in directly reducing blood sugar, but also plays an important role in dealing with the destructive effects of diabetes at the cellular and tissue level. This combination of several pathways at the same time makes black cumin a natural supplement with high potential to control diabetes. Of course, it should be noted that this medicinal plant should not be a complete substitute for doctor's prescription drugs, but can be used as an auxiliary treatment in the diet of diabetics under the supervision of an expert. How to consume black cumin in daily diet Black cumin is one of the valuable medicinal plants that has a special place in different cultures, especially in Iranian and Islamic traditional medicine. The use of this special seed, if properly and regularly included in the diet, can play an important role in controlling diabetes. To benefit from the medicinal properties of black cumin, one should pay special attention to the correct way of consumption, the right dose and the right time of consumption, because these factors have a direct effect on its effectiveness. Black cumin tea; A natural choice for blood sugar control One of the most common and natural ways to consume black cumin is to make tea. For this, it is enough to put a teaspoon of black cumin seeds in a glass of boiling water and brew it for about 10 to 15 minutes. Then you can strain it and eat it. Black cumin tea is a suitable option for daily consumption due to the quick absorption of effective compounds. Also, consuming it on a half-empty stomach or before meals can reduce blood sugar after meals and improve food digestion. This method is especially recommended for people who suffer from bloating or digestive problems. Black cumin powder; A simple but powerful combination Black cumin powder is one of the most practical forms of consuming this medicinal plant, which can be easily added to food, salad, or even mixed with honey, yogurt, and hot water. To prepare the powder, it is better to grind the cumin seeds just before consumption and store them in a closed container to prevent the oxidation of its beneficial compounds. The recommended amount of cumin powder is usually between half and a teaspoon per day. This powder contains a high concentration of thymoquinone, which is directly involved in controlling blood sugar and reducing insulin resistance. Using black cumin powder is a simple but effective way to benefit from its properties in daily life. Black cumin oil; The most concentrated source of effective compounds Oil extracted from black cumin seeds is one of the richest sources of thymoquinone, essential fatty acids and antioxidants. This oil is taken orally, and usually the recommended dose is 5 to 10 drops per day, which can be mixed with a glass of lukewarm water or food. Black cumin oil is great for people looking for stronger therapeutic effects or wanting to use a more concentrated dose. Of course, it should be used with caution, because excessive consumption may cause stomach irritation or negative effects on the liver. Choosing the original and authentic cumin oil is very important in the treatment conclusion. Pharmaceutical supplements; Black cumin capsules or tablets For people who cannot tolerate the spicy taste and specific smell of black cumin, medicinal supplements such as capsules or tablets containing black cumin extract are an ideal option. These supplements usually contain a specific dose of thymoquinone and other active ingredients and are scientifically formulated. The dosage of these supplements is usually recommended between 500 and 1000 mg per day, and it is best to take them under the supervision of a doctor or nutritionist. Black cumin capsules are a good choice for long-term use in the treatment plan of diabetic patients due to the precision in dosing and the absence of unpleasant taste. The best time to consume black cumin to control blood sugar The timing of black cumin consumption plays an important role in its effectiveness, especially in diabetic patients who need careful blood sugar control. One of the best times to use it is in the morning on an empty stomach. At this time, consuming half a teaspoon of cumin powder or a few drops of cumin oil with warm water can activate the body's metabolism and prevent a sudden increase in blood sugar at breakfast. In addition, consuming black cumin about half an hour before main meals can help reduce glucose absorption and better insulin secretion. In some special cases, it is also recommended to take black cumin at night, especially if the blood sugar is high at night, of course, this should be done with the doctor's opinion so that it does not interfere with other medications. Recommended dose of black cumin for diabetic patients The amount of black cumin to take advantage of its therapeutic properties should be adjusted based on the physical condition, type of diabetes, simultaneous medications and lifestyle of the person. In general, a good dose of black cumin powder is between 1 and 3 grams per day (roughly half to a teaspoon). Its tea can also be consumed 1 to 2 times a day. For black cumin oil, a dosage of 5 to 10 drops, once or twice a day is recommended. If you use supplements, it is common to take 500 to 1,000 mg per day, under the supervision of a specialist. The most important point is that the consumption of black cumin should be regular and continuous so that its effects in reducing blood sugar and improving insulin sensitivity appear noticeably. How to consume black cumin Black cumin is used as a complementary treatment in the control of diabetes in different forms such as tea, powder, oil and capsules. The choice of the method of consumption depends on various factors such as the patient's physical condition, severity of diabetes, eating habits and ease of use. Each of these forms introduce the active compounds of the plant into the body with different concentrations and absorption, so knowing the advantages and limitations of each method is important to achieve the best therapeutic results. Black cumin is not just a simple spice, but when used correctly, it can act as a powerful supplement along with diet and diabetes medications. Black cumin tea is one of the popular and traditional methods to take advantage of the properties of this medicinal plant. To prepare this tea, just put a teaspoon of black cumin seeds in a glass of boiling water and let it brew for 10 to 15 minutes. This bitter, but effective drink is usually consumed on an empty stomach or in the morning on an empty stomach, and it aids digestion, lowers blood sugar, and soothes the stomach. Cumin active compounds such as thymoquinone are extracted through hot water and are quickly absorbed by the body. Regular use of cumin tea can be useful in regulating blood sugar and reducing chronic inflammation in diabetic patients. ### black cumin; A natural version in the silent battle with diabetes Diabetes, the silent enemy of health, requires a multidimensional approach for effective management; From chemical drugs to lifestyle modification and healthy eating. Meanwhile, black cumin has found a special place as a plant with a historical record. This small seed with active compounds such as thymoquinone not only helps to strengthen the function of the pancreas and increase the secretion of insulin, but also makes the path of blood sugar control smoother by inhibiting sugar-increasing enzymes and reducing oxidative stress. Various consumption methods and the possibility of including it in the daily diet have made black cumin an available supplement for diabetic patients. However, it should be noted that black cumin is not a substitute for medical treatment and should be used as a complementary and safe treatment under the supervision of a doctor. Finally, remember that herbal remedies may lower blood sugar, but they may interact with your medications or have adverse effects on your liver or kidneys. Always consult your doctor before taking such substances. **To receive a visit (online or in person) with Dr. Yazdan Panah, fill out the form below**