Is MS treated by comparing Ocrelizumab and Rituximab?

Does MS have a cure, what is the result of the latest research in the treatment of MS? ============================================================================================ **Read this article to the end, you will realize that symptoms MS has a cure and certainly there is a lot of hope for a complete cure of this disease.. Some drugs such as acrylizumab and rituximab are useful in controlling the symptoms of this disease, in this article we have an overview of MS, side effects, their treatment.. Consequences.** Imagine waking up in the morning and opening your eyes to a world that is blurry for you, you go to the kitchen and get ready to eat breakfast, your body is extremely tired and your hands and feet are heavy like lead, this is the real world of those who have MS, one of the most common neurological diseases that affects many people in Iran. Read the article to the end... MS is a disease that causes damage to the nerves and brain, in this disease the nerve sheath and sheath covering the nerves called myelin is attacked, which causes loss of vision, eventually weakness, numbness and numbness. that MS patients do not have a way to live a normal life, there have been many advances in the field of MS and the existence of an effective strategy can slow down the course of the disease or control the recurrence of the disease, manage the symptoms of MS and provide psychological treatment for patients... MS has a cure New hopes in the treatment of MS There are four types of MS **(In this article, two general categories of relapsing-remitting and initial-progressing are mentioned)** The first type, also called RRMS, is known as relapsing-remitting MS and is the most common type of MS. After treatment, the patient may have relapses and attacks and symptoms.. Although efforts have been made for a long time to find a drug to treat MS, there is still no effective way to control it. In 2017, the drug aclizumab was approved by the FDA for MS patients. MS... Dr. Majid Kihani Fard Neurology Clinic ### What happens in MS In a simple explanation, in MS disease, a group of immune cells called B lymphocytes and T lymphocytes attack the myelin cells (the sheath that covers the nerves), the destruction of this sheath in the form of scars prevents proper communication between the brain and the muscles, the drug Acrelizumab actually sticks to the surface of the B cells, thus controlling these B cells.. Antibody production... less, it destroys more cells. Myelin prevents.... This drug is administered by injection and every 6 months.. According to the tests performed on progressive MS samples, this drug has been able to have effective therapeutic effects on these people, and this has increased the hope of reaching the appropriate level of treatment in these patients... MS has a cure ### The role of B lymphocyte cells in MS Many researches that were conducted on MS patients and at the site of myelin destruction, showed that the largest number of lymphocytes in the site are of T type, but the drug Acrelizumab, which is based on b lymphocytes, and the amazing results of this drug show the role of b lymphocytes in this disease, probably, according to Dr. Hazur, it plays a leading role in these cells.. Destruction of myelin cells... In fact, acrelizumab researchers look at It has changed the treatment approaches of MS and has created a lot of hope to reach the stage of cure... ### Acrelizumab compared with rituximab drug Rituximab, as an older drug than Acrylizumab, showed evidence of the effect of B lymphocytes in MS, and although it was able to have good results in the treatment of MS patients, considering that this drug was obtained from the combination of human proteins and animal proteins, after a while the cells of the body imagine and attack the animal part... But the drug Acrylizumab has been completely removed from human proteins, and such a prediction It is not true about that.... It can be said that we have not had a treatment as powerful as Acrylizumab for MS and this drug can actually stop the progress of MS... ### Rituximab drug Rituximab is a monoclonal antibody that is currently being investigated as a potent treatment for multiple sclerosis.. Rituximab is an approved treatment for a variety of leukemias and is marketed under the names Rituxan (in the US) and MabThera (in Europe).. Multiple sclerosis (MS) is gaining more attention... Apart from controlled trials Smaller, a growing number of studies in real-world populations suggest that rituximab has superior effects based on clinical and neurological outcomes in patients with relapsing-remitting MS....Additional evidence also demonstrates the efficacy of rituximab in the treatment of progressive MS phenotypes....In this topical review, we review the safety mechanism, efficacy, and available evidence..Other clinical aspects of rituximab in the treatment of MS... Finally, We highlight gaps in current knowledge and the need for comparative studies with other disease-modifying approaches in MS... #### How does rituximab work?.. Rituximab is a monoclonal antibody (a protein designed to target and bind to a specific protein) that interferes with the growth and spread of lymphoma blood cancer cells.. It targets the CD20 antigen, a substance that It is found on the surface of special immune cells called B cells. Rituximab binds to the antigen on the cell surface, because many B cells are involved in B cell death. Sclerosis, rituximab may be useful for treating this disease.. Amount and ability to consume RITUXAN is a clear, colorless solution for intravenous injection: - 100 mg / 10 ml in a disposable syringe - 500 mg / 50 ml in a disposable syringe #### Why the strength of Zumab Acrylic does not make this drug spread faster and become available to patients Although the mentioned drug has appeared as a strong drug and the research results show all the evidence in its favor, but considering that the results of the side effects of the drug are not yet available, and in principle, doctors are somewhat resistant to its use until the full results of the drug are obtained, and they want to be sure of the health and safety of their patients in relation to the drug, and also the high price of the drug is one of the things that make insurance companies cooperate for it.. ### Which type of MS is this drug effective in treating? It was said that acrelizumab has had acceptable results for both relapsing-remitting and progressive MS, although its effects have been reported to be 25% in the progressive type, but according to Dr. Hazor, these results could be a threshold for achieving a good level of treatment for MS patients, and according to Dr. Havers, we are on the verge of entering an era where stopping and treating advanced MS will be available, but we are not there yet. MS has a cure Sources: