Dr. Shahram Sawad
Karaj
کد عضویت: System code: 87050
Lobular breast cancer, which is also called invasive lobular carcinoma, is a type of breast cancer that originates from the milk-producing glands or milk ducts and spreads in the breast tissue.. ductal breast ** (invasive ductal carcinoma)
In lobular breast cancer, the cells grow in a linear fashion, but in the ductal type, the cancer cells form a mass-like structure... Who gets lobular breast cancer?
The probability of getting this cancer is higher in women after the age of 55.... This type of cancer is also rarely seen in men.... Lobular breast cancer occurs at older ages.... Most cases of this type of cancer are diagnosed after the age of 60... Symptoms of lobular breast cancer
In most cases, this type of cancer has no symptoms and is identified only by observing the suspicious mass by the doctor during mammography screening.... In some cases, you or your doctor will notice the swelling of a part of the breast... Of course, unlike other types of breast cancer, in invasive ductal cancer, the first hard lump in the breast tissue cannot be felt.
- Redness of the skin
- indentation
- Breast or nipple pain
- Discharge from the nipple
- Redness or roughness of the skin or nipple
- Swelling or stiffness under the armpits
Diagnosis of lobular breast cancer
Different methods are used to diagnose invasive lobular carcinoma:
- Physical examination of the breast
- Mammography
- Biopsy
- Ultrasound
- Breast MRI
The cause of lobular breast cancer
Doctors believe that this type of cancer is caused by genetic changes in the DNA of cells.. but the cause of these changes is still unknown.. Various factors play a role in this type of cancer:
- Age... Most people with this type of cancer are over 55 years old.... - Hormone therapy... The chance of developing this type of cancer is higher in women who have undergone hormone therapy after menopause... - Genetic factors... Some genes play an important role in causing cancer... For example, hereditary diffuse gastric cancer is a rare type of cancer that is associated with an increased risk of lobular breast cancer and gastric cancer.. Classification of lobular breast cancer
Based on the size of the tumor, the presence or absence of hormone receptors, the cancerous mass is placed in stages 1 to 4. This information plays a very important role in the prognosis of the disease and the choice of treatment. Stages 2, 1 and 3 are the initial stages of cancer, but in stage 4, other organs such as bones or liver are also involved in his general report. Lobular breast cancer includes:
- Tumor size
- Nottingham degree
Tumor necrosis factor
- Margin or border of the tumor
- Involvement of lymphatic vessels
- Status of lymph nodes
- Status of hormone receptors
- HER2 status
- Determination of cell proliferation rate (Ki-67 marker)
Treatment of lobular breast cancer
### Surgery
Based on the characteristics of the tumor cells and your medical history, the type of surgery is determined by the doctor... ### Radiotherapy
It is recommended after almost all cases of lumpectomy and sometimes after mastectomy if the lymph nodes are also involved.... ### Chemotherapy
Chemotherapy is done before or after surgery. The doctor determines the time based on the type of breast cancer and your medical history. ### hormone therapy
In cases where cancer cells have receptors for estrogen, progesterone, or both, the doctor recommends hormone therapy. It is also called hormone therapy, anti-estrogen therapy, or endocrine therapy. This treatment reduces the amount of estrogen or prevents it from binding to cancer cells. are, it prevents their growth.... Some targeted drugs have the same behavior as antibodies that are naturally produced by the body's immune system.... These drugs are also called immune-targeted therapy.... ### i
Immunotherapy destroys cancer cells by activating the body's immune system. The characteristics of cancer cells determine the effectiveness of immunotherapy.. If the cancer cells have spread to the surrounding tissues, the 5-year survival rate in them reaches 9%, and in other cases, the cancer reaches 9%. The 5-year survival rate is 22%.
- Classic ILC is the most common type of this cancer, which includes small tumor cells that have spread to the stroma, fat tissue, glands and milk ducts. (Tubulolobular ILC) cells grow linearly and some of them look like small tubes... Color